Amiodarone

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Amiodarone pneumonitis.

Amiodarone is an iodinated benzofuran derivative that is widely used for the treatment of cardiac arrhythmia. The drug has an extensive adverse effect profile that involves the liver, thyroid, cornea, skin, lung, bone marrow, and neuromuscular system. Pulmonary toxicity is the most serious adverse reaction, and it often limits the drug’s clinical use.1,2 We encountered a patient with suspected ...

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Intravenous amiodarone.

Intravenous amiodarone was approved in 1995 for the treatment of malignant and resistant ventricular arrhythmia. Although it is an "old drug," much has been learned recently about this complex drug and its application in a variety of cardiac arrhythmias. The objectives of this review were to summarize what is known about intravenous amiodarone, including its pharmacologic and electrophysiologic...

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Hepatocellular toxicity and pharmacological effect of amiodarone and amiodarone derivatives.

The aim of this work was to compare hepatocellular toxicity and pharmacological activity of amiodarone (2-n-butyl-3-[3,5 diiodo-4-diethylaminoethoxybenzoyl]-benzofuran; B2-O-Et-N-diethyl) and of eight amiodarone derivatives. Three amiodarone metabolites were studied, namely, mono-N-desethylamiodarone (B2-O-Et-NH-ethyl), di-N-desethylamiodarone (B2-O-Et-NH(2)), and (2-butyl-benzofuran-3-yl)-(4-h...

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Amiodarone in Pediatric Patients

Recent interest in cardiac arrhythmias in children has been motivated by a growing awareness and understanding of primai}^ rhythm disorders in the young as well as by an increasing emergence of cardiac arrhythmias following surgical repair of many congenital heart defects.̂ An increased understanding and use of both conventional and investigational antiarrhythmic medications in children has, by ...

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Amiodarone-induced thyroid dysfunction.

To purchase electronic or print reprints, contact The InnoVision Group, 101 Columbia, Aliso Viejo, CA 92656. Phone, (800) 809-2273 or (949) 362-2050 (ext 532); fax, (949) 362-2049; e-mail, [email protected]. stated that he did not feel well, and before admission, he had had an episode of unexplained profuse diaphoresis, rapid heart beat, and shortness of breath. He also said that he had lost ab...

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ژورنال

عنوان ژورنال: Reactions Weekly

سال: 2021

ISSN: ['1179-2051', '0114-9954']

DOI: https://doi.org/10.1007/s40278-021-98152-7